Molecular diagnostics and treatment of pancreatic cancer : systems and network biology approaches
/ edited by Asfar S. Azmi
- xx, 446 pages : illustrations
Includes bibliographical references and index.
Section I. Current trends and advances in pancreatic cancer Epidemiology, treatment, and outcome of pancreatic cancer Advances in primary cell culture of pancreatic cancer Multimodal therapies for pancreatic cancer The role of Notch signaling pathway in the progression of pancreatic cancer Section II. Gene expression profiling and bioinformatics analysis in pancreatic cancer Bioinformatics analysis of pancreas cancer genome in high-throughput genomic technologies Statistical analysis of high-dimensional data for pancreatic cancer Gene expression profiling in pancreatic cancer Genetic susceptibility and risk of pancreatic cancer Section III. Pancreatic cancer proteomics Proteomics in pancreatic cancer translational research Proteomic differences and linkages between chemoresistance and metastasis of pancreatic cancer using knowledge-based pathway analysis RNAi validation of pancreatic cancer antigens identified by cell surface proteomics Section IV. Systems and network understanding of pancreatic cancer signaling The significance of the feedback loops between Kras and Ink4a in pancreatic cancer Systems biology of pancreatic cancer stem cells Characterizing the metabolomic effects of pancreatic cancer Prioritizing diagnostic, prognostic, and therapeutic microRNAs in pancreatic cancer : systems and network biology approaches Section V. Systems approaches to pancreatic cancer therapeutics Integration of protein network activation mapping technology for personalized therapy : implications for pancreatic cancer Computational and biological evaluation of radioiodinated quinazolinone prodrug for targeting pancreatic cancer Systems and network pharmacology strategies for pancreatic Ductal adenocarcinoma therapy : a resources review