TY  - BOOK
AU  - Binda,Olivier
AU  - Fernandez-Zapico,Martin Ernesto
TI  - Chromatin signaling and diseases
T2  - Translational epigenetics series
SN  - 9780128023891
U1  - 572.87 
PY  - 2016///]
CY  - London
PB  - Academic Press
KW  - Chromatin
KW  - Epigenesis
N1  - Includes bibliographical references and index; Histone acetyltransferases, key writers of the epigenetic language; Impacts of histone lysine methylation on chromatin; The role of histone mark writers in chromatin signaling : protein arginine methyltransferases; Histone kinases and phosphatases; The bromodomain as an acetyl-lysine reader domain; Chromo domain proteins; The role of PHD fingers in chromatin signaling : mechanisms and functional consequences of the recognition of histone and non-histone targets; Tudor domains as methyl-lysine and methyl-arginine readers; Histone deacetylases, the erasers of the code; Lysine demethylases : structure, function, and disfunction; Variation, modification, and reorganization of broken chromatin; Cross-talk between histone modifications integrates various signaling inputs to fine tune transcriptional output; Signaling and chromatin networks in cancer biology; Crosstalk between DNA methylation and chromatin structure; Epigenetic regulation of endoplasmic reticulum stress; Chromatin signaling in aging and cellular senescense; Chromatin dynamics and epigenetics of stem cells and stem-like cancer cells; Altered chromatin signaling in cancer; Impact of chromatin changes in pathogenesis of infectious disease : a pathogen view; Chromatin remodeling and epigenetic reprogramming in chronic disease and cancer in the liver and pancreas; Pharmacological and therapeutic targeting of epigenetic regulators; Use of chromatin changes as biomarkers; Regulation of host chromatin by bacterial metabolites
ER  -